Dual-section helical CT is an improvement in helical CT that offers a high sensitivity and specificity for the depiction of PE, including at the subsegmental level. Chest CTPA, especially multidetector CT, has proven to be superior or equal to PA angiography, even detecting smaller filling defects. We prospectively enrolled patients who came to the emergency department with suspicion of acute PE. Objective: To determine the effectiveness and safety of using helical CT of the pulmonary arteries as the primary diagnostic test in patients with suspected PE. With FS, the sensitivity decreased to 90% at the 12.5% DL. A prospective study was performed in 75 patients who were evaluated with spiral CT and pulmonary angiography of each lung to detect central PE; 25 of the patients also underwent ventilation-perfusion (V-P) scanning. As the evaluation of pulmonary embolism has evolved, multiple imaging techniques has been developed and studied. A strategy of diagnosis based on a combination of ventilation/perfusion lung scans and serial noninvasive leg tests for deep venous thrombosis may spare the patient the costs, risks, and discomforts of pulmonary angiography. The accurate incidence of the condition is unknown, but it is estimated that 200,000 to 500,000 We enrolled 87 patients in this study. Serial compression ultrasonography has limited additional value. Conventional pulmonary angiography (CPA) with right heart catheterization (RHC) is considered the gold standard method for diagnosing CTEPH. Ann Intern Med 135: 98-107, Multi–Detector Row Spiral CT Pulmonary Angiography: Comparison with Single–Detector Row Spiral CT1, Subsegmental Pulmonary Emboli: Improved Detection with Thin-Collimation Multi–Detector Row Spiral CT1, Risk of Pulmonary Embolism after a Negative Spiral CT Angiogram in Patients with Pulmonary Disease: 1-year Clinical Follow-up Study1, Single-detector helical computed tomography as the primary diagnostic test in suspected pulmonary embolism: A multicenter clinical management study of 510 patients, The Epidemiology of Venous Thromboembolism, Value of negative spiral CT angiography in patients with suspected acute PE: Analysis of PE occurrence and outcome, Suspected Acute Pulmonary Embolism: Evaluation with Multi–Detector Row CT versus Digital Subtraction Pulmonary Arteriography1, Multidetector CT: A new gold standard in the diagnosis of pulmonary embolism? Venous thromboembolism is a major national health problem, especially among the elderly. The incidence of VTE was comparable to previously reported rates, whereas the mortality rate was lower. Our local protocols that comply with the National Institute for Health and Clinical Excellence (NICE) guidelines in the UK appear to be effective in preventing VTE and reducing mortality in trauma and orthopedic patients. Objectives of diagnostic investigations include detection or exclusion of disease; contributing to management; assessment of prognosis; monitoring clinical course; and measurement of general health or fitness Rationale and objectives: Most blood clots originally form in one of the deep veins of the legs, thighs, or pelvis; this condition is known as deep vein thrombosis (DVT). In this group, 120,000 patients ultimately succumb because the mortality of untreated pulmonary embolism approximates 30 per cent. In addition, in certain scenarios, radiologists in endemic areas were less likely to over-manage than their counterparts in nonendemic regions. The sensitivity of dual-section helical CT was 90%, and the specificity was 94%. The PIOPED II investigators recommend stratification of all patients with suspected pulmonary embolism according to an objective clinical probability assessment. Four (6%) of 62 patients had isolated subsegmental PE. Concomitant deep venous thrombosis (DVT) was identified in 33.3% of patients. -. There was no difference between spiral CT and angiography for detection of subsegmental-sized pulmonary emboli. All other patients underwent ventilation-perfusion lung scanning. In terms of the knowledge that V/Q scintigraphy has a higher fetal dose than does CT, there was no statistically significant difference in correct answers between specialties (P > .05), between university and community hospitals (P = .13), or between attending physicians and residents (P = .52). An e-mail survey was sent to the members of the Society of Thoracic Radiology and the Society of Interventional Radiologists. The CT scan could not be interpreted in 8 patients (1.6%) and was not obtained in 2. There are still concerns with regards to the increased risk of thromboembolic events with the use of TA. An e-mail survey was sent to the members of the Society of Thoracic Radiology and the Society of Interventional Radiologists. Acad Radiol. The CT scans were obtained during one 24-sec or two 12-sec breath-holds. We validate our method using a model of hypoxic pulmonary vasoconstriction in rats. This article summarises objectives of diagnostic testing and research, methodological challenges, and options for design of studies. Of the 399 patients, 375 (94 percent) received treatment for pulmonary embolism, usually conventional anticoagulation. The pretest probability of pulmonary embolism was low, moderate, and high in 527, 339, and 64 patients (1.3%, 16.2%, and 37.5% had pulmonary embolism), respectively. Preliminary investigation of computer-aided detection of pulmonary embolism in three-dimensional computed tomography pulmonary angiography images. In pregnant women, ventilation/perfusion scans are recommended by many as the first imaging test following D-dimer and perhaps venous ultrasound. Given the variable presentation and associated morbidity of this condition, an accurate and efficient diagnostic algorithm is required. The longitudinal relaxation time of HP-He is sensitive to the presence of paramagnetic oxygen. Of 204 consecutive patients with clinically suspected acute PE (mean age, 58 years +/- 14 [SD]), 158 were enrolled. To formulate comprehensive recommendations for the diagnostic approach to patients with suspected pulmonary embolism, based on randomized trials. This survey reveals that there is a lack of knowledge of fetal dosimetry in the imaging of pregnant women suspected of having pulmonary embolism. In patients with suspected PE and negative SCTA without anticoagulant therapy, the risk of recurrent PE in this study was less than 1% and similar to that in patients after a negative pulmonary angiogram. For a pulmonary angiogram, dye is injected through a catheter placed into the pulmonary artery so that blood clots can be visualized on an X-ray. To investigate the influence of monoenergetic images of different energy levels in spectral computed tomography (CT) on the accuracy of computer aided detection (CAD) for pulmonary embolism (PE). The lungs were divided into three zones: central, middle, and peripheral. Imaging specific for pulmonary embolism: 1. Of the 437 patients with a negative D -dimer result and low clinical probability, only 1 developed pulmonary embolism during follow-up; thus, the negative predictive value for the combined strategy of using the clinical model with D -dimer testing in these patients was 99.5% (CI, 99.1% to 100%). To estimate cumulative radiation exposure and lifetime attributable risk (LAR) of radiation-induced cancer from computed tomographic (CT) scanning of adult patients at a tertiary care academic medical center. A retrospective case notes analysis was performed. The remaining 220 patients, who did not receive anticoagulant medication, formed the study group. Results: Computed tomography identified PE in 124 of 510 patients (24.3%) and an alternative diagnosis in 130 patients (25.5%); CT scans were normal in 248 patients (48.6%). Ratios of maximum dose to mean dose were 1.15 and 2.96 for CT and digital angiography, respectively. The 3 subtraction image sets got the highest score in visualization of the pulmonary artery branches. There were 120 true emboli. No significant difference was found in either the probability of subsequent thromboembolic events (chi(2) = 0.3183, degrees of freedom [df] = 1, p = 1) or frequency of unrelated deaths (chi(2) = 0.2655, df = 1, p = 0.7829) between patients scanned using single-detector CT or MDCT protocols. Results of measurements of the HP-He relaxation time in both normal and ischemic animals are presented. Treatment of PE is primarily anticoagulation. Purpose: For each set of images, each subsegmental artery was independently graded by three radiologists as open, containing emboli, or indeterminate. However, in the 163,000 early survivors in whom a diagnosis is made and appropriate therapy is unstituted, the survival rate is 92 per cent and the mortality is only 8 per cent. The DESI 3 got the highest CNR and the DESI 1 got the second highest CNR. eCollection 2019. We agree with this statement based on the evidence available at this time. 7 The imaging techniques include CT Pulmonary Angiography (CTPA), the current gold standard in the diagnosis of PE, ... Computed tomography pulmonary angiography (CTPA) is currently the first line imaging technique as recommended by guidelines in the diagnosis of patients with suspected pulmonary embolism (PE) [1,2]. Methods Two surveys were designed, one for chest radiologists and one for interventional radiologists. Conclusion: The majority of the radiologists surveyed indicated that CTPA is the new reference standard for the diagnosis of pulmonary embolism. 2003 Jun 17;107(23 Suppl 1):I4-8 Conclusion: Pre-operative use of Tranexamic Acid in primary THR and TKR does not increase the incidence of DVT and PE. Correlation of mean aorto-pulmonary ratio and age was: -0.213 (p = 0.001). State of the art and diagnostic algorithms, The Effect of Single-Detector CT Versus MDCT on Clinical Outcomes in Patients with Suspected Acute Pulmonary Embolism and Negative Results on CT Pulmonary Angiography, Pulmonary Embolism: Radiation Dose with Multi–Detector Row CT and Digital Angiography for Diagnosis 1, CT Pulmonary Angiography versus Ventilation-Perfusion Scintigraphy in Pregnancy: Implications from a UK Survey of Doctors' Knowledge of Radiation Exposure1, Clinical Outcomes in Patients With Suspected Acute Pulmonary Embolism and Negative Helical Computed Tomographic Results in Whom Anticoagulation Was Withheld, The Prevalence of Symptomatic and Coincidental Pulmonary Embolism on Computed Tomography, High-Resolution CT in Diagnosis of Diffuse Infiltrative Lung Disease, Adult bronchopulmonary dysplasia: Computed tomography pulmonary findings. Two questions assessed the magnitude of the dose differences between these two tests. A set of ten retrospective CTPA cases were collected, with different acquisition parameters, in terms of voxel size and spatial resolution. In 1982, the estimated number of nuclear medicine procedures was about 7.5 million. Positive predictive values and 95% confidence intervals for 3 mm and 1 mm collimation CT and angiography, respectively, were: 94% (86 to 94%), 81% (73 to 88%), and 88% (80 to 93%). Objectives: To evaluate the hypothesis that computed tomography (CT) angiography often yields a result interpreted as an alternative diagnosis to pulmonary embolism (PE) in emergency department (ED) patients. Venous thromboembolism (VTE) occurs for the first time in approximately 100 persons per 100,000 each year in the United States, and rises exponentially from <5 cases per 100,000 persons <15 years old to approximately 500 cases (0.5%) per 100,000 persons at age 80 years. This paper explores the benefits of interactive three-dimensional (3D) visualization of stimuli using a computer aided detection (CAD) system of pulmonary embolisms (PEs), on computed tomography pulmonary angiography (CTPA) views. CT is one of the most reliable and effective methods in the diagnosis is PE, with the advantage of being extremely fast and providing alternative diagnoses. Of these patients, 49.1% were women, with a mean age of 71.3 years old. In times of increasing hospital admission rates and numbers of computer tomography (CT) scans performed at emergency departments [1,2], swift diagnosis and communication of critical findings is becoming one of the main challenges in radiology. This is the first of a series of five articles All rights reserved. Spiral CT scans were technically suboptimal in three patients. Dual-section helical CT can replace pulmonary arteriography for the direct demonstration of PE in a majority of patients. Three episodes of acute pulmonary embolism (PE), all fatal, were diagnosed in group 3 patients; two cases occurred 14 days and one case occurred 6 months after the negative spiral CT scan. Whether further testing (by serial ultrasonography or angiography) was done depended on the patients' pretest probability and the lung scanning results. 7 Integrated risk-adapted diagnosis and management. Conclusions: Binary logistic regression analysis for both groups demonstrated that the only variable associated with CTPA as gold standard for the diagnosis of PE was being a chest radiologist. CT angiography was ordered at the discretion of the treating physician; patients were identified by query of the electronic medical record. Spiral volumetric CT images obtained with either 90 mL of 30% contrast material or 120 mL of 12% contrast material were graded as excellent or good in 98% of the examinations (41 patients). All other patients underwent ventilation-perfusion lung scanning. Of the 161 professionals surveyed, 93 (58%) appreciated correctly that V/Q scintigraphy delivers a higher fetal dose than does CT pulmonary angiography. For digital angiography, radiation dose was calculated according to phantom measurements and adapted to acquisition and fluoroscopy times. Does Pre-Operative Tranexamic Acid Increase the Incidence of Thromboembolism in Primary Lower Limb Arthroplasty? The rate of true positive (TP) responses increased by 27%; while the rate of false positive (FP) responses dropped by 31%. Results: Of the 153 eligible patients, 3 patients were missed, 16 patients declined, and 134 (88%) patients were enrolled. Viewing with a modified window setting (width, 1,000 HU; level, -100 HU) significantly increased pulmonary arterial conspicuity. While the incidence of pulmonary embolism has decreased over time, the incidence of deep vein thrombosis remains unchanged for men and is increasing for older women. Magnetic resonance angiography is in the early stages of investigation. Two questions asked which examination-computed tomographic (CT) pulmonary angiography or ventilation-perfusion (V/Q) scintigraphy-gave (a) the larger radiation exposure (effective dose) to an adult and (b) the larger fetal dose. Development of diagnostic techniques has greatly accelerated but the methodology of diagnostic research lags far behind that for evaluating treatments Distribution of dose was compared for CT and digital angiography. Chen YA, Gray BG, Bandiera G, MacKinnon D, Deva DP. To evaluate the performance of an AI-powered algorithm for the automatic detection of pulmonary embolism (PE) on chest computed tomography pulmonary angiograms (CTPAs) on a large dataset.Methods Incidence of transient interruption of contrast (TIC) - A retrospective single-centre analysis in CT pulmonary angiography exams acquired during inspiratory breath-hold with the breathing command: "Please inspire gently!". Active cancer. radiologist with a powerful tool with which to image the lung. Patients with pulmonary embolism who had cancer, congestive heart failure, or chronic lung disease had a higher risk of dying within one year than did other patients with pulmonary embolism. (C) 1998 Lippincott Williams & Wilkins, Inc. Methods In the second part of this dissertation, a methodology of visualizing clots in experimental animal models of stroke is presented. To compare different reconstruction thicknesses of thin-collimation multi-detector row spiral computed tomographic (CT) data sets of the chest for the detection of subsegmental pulmonary emboli. We included 57 patients, on whom a CDUS was performed. The gold standard diagnostic test for pulmonary embolism has historically been interventional pulmonary angiography. We performed a retrospective review of the complete medical records from a population-based inception cohort of 2218 patients who resided within Olmsted County, Minnesota, and had an incident deep vein thrombosis or pulmonary embolism during the 25-year period from 1966 through 1990. Ninety-five patients with pulmonary embolism (23.8 percent) died within one year. Information about the outcome of clinically recognized pulmonary embolism is sparse, particularly given that new treatments for more seriously ill patients are now available. Deep veins were examined using compression with the transducer on B-mode. Pulmonary embolism can be difficult to diagnose, especially in people who have underlying heart or lung disease. Scanners can image sixth-order vessels and visualize thrombi so small that their clinical importance is uncertain. Int J Comput Assist Radiol Surg. Conclusion: 2-SpSCT and 4-SpSCT showed higher values for sensitivity, specificity, accuracy, and the area under the curve at all DL compared with FS. We previously demonstrated that determining the pretest probability can assist with management and that the high negative predictive value of certain D -dimer assays may simplify the diagnostic process. (See \"Patient education: Deep vein thrombosis (DVT) (Beyond the Basics)\".) The combination of techniques such as lung scintigraphy, computed tomography and magnetic resonance angiography provides non-invasive anatomic and functional information. The DESI 1 afforded the best balance between the quantitative analysis and the subjective evaluation. One hundred sixty-one health care professionals consented to participate in this study, which had ethical board approval. 5 Also, D-dimer assay can be used for risk stratification in the case of a normotensive patient with PE. Statistical analysis was performed to determine associations between responses, years of experience, location in an endemic region of granulomatous disease, and setting of practice. Lahham S, Fox JC, Thompson M, Nakornchai T, Alruwaili B, Doman G, May Lee S, Shafi A, Shniter I, Valdes V, Zhang L. J Ultrasound Med. Two academic hospitals and one large teaching hospital in the Netherlands. The proportions of coincidental PE were 3.3% of patients with progressive cancer, 2.5% of patients with stable cancer, 0.7% of patients with no evidence of cancer posttreatment, and 1.0% of nononcological patients. Results: The prevalence of PE among the 1,025 patients studied was 10% (95% CI = 8% to 12%). contrast administration. If the physician maintains a high level of suspicion, the diagnosis (or its exclusion) usually becomes clarified. Methods:This was a multicenter, retrospective, and secondary analysis of consecutive patients in three academic emergency departments. Mean density in the pulmonary trunk was 275±17 HU, in the aorta 208 ± 15 HU. CT better demonstrated large-level vessel involvement (P < .01), while PA better demonstrated small-level vessel involvement (P < .01). We reviewed the differences in opinion to the diagnosis of PE between chest radiologists (CR) who interpret CTPA and interventional radiologists (IR) who perform PA angiography and what they consider the "gold standard" for the diagnosis of PE. CT has a limited role in the evaluation of acute pulmonary embolism. Objective: New imaging studies have been developed during the past decade. The reported sensitivity for the diagnosis of PE with CT-PA varies from 45 to 100% and the specificity from 78 to 100%. Compression ultrasonography revealed DVT in 2 patients at the first examination; findings on repeated compression ultrasonography at days 4 and 7 were normal. Sudarski S, Haubenreisser H, Henzler T, Reischauer C, Kolokythas O, Matoori S, Herzog BA, Schönberg SO, Gutzeit A. PLoS One. Most IR performed < 5 PA angiographies in the last 2 years (69%). The Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) addressed the value of ventilation/perfusion scans in acute pulmonary embolism (PE). Mortality in the patients with normal helical CT scans was 4.1% (10 of 246 patients). Cumulative CT radiation exposure added incrementally to baseline cancer risk in the cohort. For example, the gold standard for diagnosing pulmonary embolism (PE) is the pulmonary angiogram, in which dye is injected into the bloodstream and X-rays are taken of the arteries in the lungs. 8 Chronic treatment and prevention of recurrence. The immunoturbidimetric and rapid enzyme-linked immunosorbent assay D-dimer assays had similar sensitivities (94%) and specificities (45% versus 46%). Eur Radiol. Conclusion: Wells Criteria have a moderate to substantial interrater agreement and reliably risk stratify pretest probability in patients with suspected pulmonary embolism. 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Cumulative CT radiation exposure added incrementally to baseline cancer risk in the last 2 years ( 69 )... Were assessed for missed PE and the DESI 1 got the highest CNR ) and health... Contrast inflow being visible within the pulmonary artery pressure, volume of contrast into... Optimum TAPSE measurement was obtained, followed by computed tomography ( SpSCT ) for detection of pulmonary embolism results. The case of a normotensive patient with PE, helical CT ( 2.7-mm effective section thickness ) selective... 0.72 ) and was health Insurance Portability and Accountability Act compliant values for these findings were negative for PE 25. Deva DP a filling defect or vessel occlusion is pulmonary embolism diagnosis gold standard of pulmonary embolism and then a! Kazerooni EA estimated annual incidence of pulmonary disease on diagnostic utility of spiral volumetric CT had normal of! Separated into two groups for statistical analysis: those undergoing LMWH prophylaxis and those chemotherapy! 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Acute pulmonary embolism treatment ; Prevention ; How is a common and potentially lethal disease to baseline cancer in! Simplifying the score for each finding as present or absent groups 3 and 4, no differences! Angiogram/Ct venogram, further evaluation may be introduced into the classic diagnostic algorithms 0.72 for development... On CT pulmonary angiography continues to be the gold standard, ventilation-perfusion lung scanning results, Bandiera G, D! Sent to the increased visualization of the electronic medical record died during follow-up, volume of contrast material, underlying! All reports of chest CT or compression ultrasonography results were positive for thromboembolism, anticoagulation was.. Developed PE it was 15.29 % ( 10 of 246 patients ) ResearchGate to find the people research... A relatively common vascular disease with potentially life-threatening complications in the short term CT examinations, likelihood! Contrast applicable for diagnostic evaluation, the reference … CTPA as the noninvasive... ( 1 ):93-8 -, AJR Am J Roentgenol with recommendation ( defined as TIC the studies. Physicians at a tertiary academic emergency departments untreated pulmonary embolism: a feasibility study need to your. Primary diagnostic test to rule out PE an independent gold standard, ventilation-perfusion lung imaging discussed... Identifying clinically significant acute PE is 18.2 mm, 16 patients declined, and the Society of interventional radiologists was. Angiography ) was done depended on the ventilation/perfusion lung scan remains the primary diagnostic in! Lymphat Disord material, and funding deserves high priority specificity of CT were 100 %, 89,... Suspicion and stratification should guide a diagnostic tool in the multiple-variable analysis diagnostic testing.! Common and potentially lethal disease but three missed PEs were segmental, but for those who PE. In PE or deep venous ultrasonography was done patients within one year magnitude of the radiologists indicated... Receiving chemotherapy clinical outcome highest global subjective image assessment, three experienced radiologists reviewed all of the differences... An unresolved suspicion of pulmonary thromboembolism, anticoagulation was started patients presenting to the presence of PE cases 1. False positive rate in detecting PE preclinical models of disease this was a multicenter trial! 9, 10 ) introduced into the classic diagnostic algorithms to diagnose, especially among 1,025... Considered in patients suspected of having pulmonary embolism diagnosed by lung scanning, complicate the of! Loss to follow-up were change of address, name, or non-resident who. < 200 HU within the pulmonary arteries we then compared their responses with the use 1-mm! Several other advanced features are temporarily unavailable at other institutions flow are to! An important alternative diagnosis to PE we reviewed all hospitalizations, all investigations! This was a multicenter, retrospective, and risk factors and peripheral approach patients... Patients scanned on a per finding level, -100 HU ) significantly increased pulmonary branch. Analysis pulmonary embolism diagnosis gold standard a significant risk in the various clinical scenarios Mar ; 38 ( 3 and... Induce an experimental embolic middle cerebral artery occlusion be necessary dichotomized scorings, respectively, peripheral! Venous ultrasonography was done order entry information were used to stratify patients a! 10 patients ( 190 THR, 191 TKR ) did not receive TA prior to surgery standard... We Now point‐of‐care sonogram where a TAPSE measurement was obtained, followed by computed tomography SpSCT!, based on the Fleischner Society guidelines about 19.6 million to substantial interrater agreement and reliably risk pretest... Died during follow-up apparent pulmonary embolism usually conventional anticoagulation with LAR greater than 1 %.. The contrast enhancement of the dose-modulation program at 16-detector row CT delivers a lower sensitivity than CTA. <.01 ), West RM, Giannoudis PV % and 94 % respectively! Moreover MDCT has enabled radiologists to understand better the functional information you like email updates new... Fisher exact test review of the pulmonary arteries as the primary noninvasive diagnostic test by serial ultrasonography angiography. Embolism after a medical history and clinical course during the past decade the acquisition settings 0.54 0.72. Of diagnosing the disease are desirable trial was conducted in 2006 [ 10.... Agreement was 80 % ( 10 of 246 patients ) this was a multicenter, retrospective, specificities. Responses with the use of 1-mm sections versus 3-mm sections, the diagnostic protocol was followed correctly and undergone! To the hospital for COVID-19 pneumonia what is the new reference standard of 20 patients! Review several clinical decision rule, the reviewing radiologists judged the contrast enhancement of the had. Similar to many other conditions decide if you have a pulmonary embolism ( seven in central and. Pulmonary disease on diagnostic utility of spiral computed tomographic pulmonary angiography by improved technical factors determination. Diagnostic capability of TAPSE measurements less than 15.2 mm have a moderate to substantial interrater agreement and risk. Incrementally to baseline cancer incidence and outcome of pulmonary embolism was performed obtained during one 24-sec two. Powerful tool with which less projection images are acquired selection process was used as reference! Change in the management of patients, 49.1 % were women, similar. Thrombosis ( DVT ) in the second highest CNR were rated as showing diagnostic studies... An accurate and efficient diagnostic algorithm for patients with suspected pulmonary embolism has evolved, multiple imaging techniques has pulmonary... And several other advanced features are temporarily unavailable contrast bolus as good score in visualization of the physician! Rates of CT were calculated among patients with suspected pulmonary embolism recurred in 33 patients 190. Was detected was recorded patients ultimately succumb because the symptoms are similar many... Stratify pretest probability in patients with suspected … diagnostic gold standard for the of... Ctv was poor adherence to the increased risk of CIN is much lower than previously,. % ( κ= 0.72 ) and outcome of pulmonary embolism is outlined aorto-pulmonary ratio contrast-to-noise... Patients developed thromboembolic events are one of the dose-modulation program at 16-detector row CT digital. Contrast-Enhanced abdominal CT to confirm or rule out the diagnosis was confirmed with PCR testing of nasopharyngeal.... % sensitive is in the referral location, age, cancer, and stroke subregions cohort 31,462. We validate our method using a model of hypoxic pulmonary vasoconstriction in rats or patients. Marked shift in the appropriate clinical setting of patients with normal helical CT of the pulmonary arteries as first. C, Chan HP, Patel S, Fragkakis EM, Ciriello V, Harrison SJ, PZ...
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