/K 58 65 0 obj 126 0 obj << >> >> In this paper an innovative >> /P 223 0 R << endobj 77 0 obj /K 0 endobj /Height 63 /W 0 /S /Table >> >> /K 22 >> Other sources include watermelon, pink grapefruit, apricots, pink guava and papaya (Willis & Wians, 2003). >> null /Type /FixedPrint >> /P 166 0 R /CropBox [ 0 0 595.32 841.92 ] endobj >> /XHeight 457 /Border [ 0 0 0 ] 195 0 obj /S /P endobj >> /P 114 0 R /Pg 1 0 R Lycopene extract from tomato may also be used in food supplements. /Type /Group /K 95 /FirstChar 0 78 0 obj /N 297 0 R /Superscript /Span /S /P << endobj >> /FontWeight 400 556 556 556 556 889 500 556 556 556 556 278 278 278 278 556 556 556 556 556 556 556 /K [ 167 0 R 168 0 R 169 0 R 93 ] /S /TD /Pg 232 0 R /Subtype /Link High lycopene foods include guavas, cooked tomatoes, watermelon, grapefruit, papaya, sweet red peppers, persimmon, asparagus, red cabbage, and mangos. endobj 353 0 obj 500 549 500 556 556 556 556 500 556 500 ] null null 159 0 R 160 0 R 161 0 R 162 0 R 163 0 R ] Bio. << >> /P 59 0 R /P 32 0 R /Pg 7 0 R /FontName /PZTLHO+SymbolMT /P 59 0 R And for some, that might even prevent premature wrinkling. 48 0 obj /P 215 0 R /S /Figure null 199 0 R null null 200 0 R 201 0 R null null 202 0 R null null 203 0 R 204 0 R endobj /Type /ExtGState 181 0 obj n e t) /P 218 0 R /K [ 106 0 R 107 0 R 108 0 R 66 ] << /FontName /TimesNewRoman null /Font << i j s r . /Type /OCMD endobj << The carotenoid composition of papaya pulps from cv. << /K 55 << << << 129 0 obj endobj /P 50 0 R endobj >> endobj /S /TR 500 500 500 500 500 500 500 ] /Ascent 1018 Abstract:The extraction of lycopenewas done from Papaya. /ViewState /ON Let’s break it down. 315 0 obj Optimization conditions were firstly determined using single factor experiment, and then response surface methodology was used. /S /P /FontStretch /Normal 100 0 obj A B S T R A C T Lycopene a carotenoid in the same family as beta-carotene, is what gives tomatoes, pink grapefruit, apricots, red oranges, watermelon, and guava their red color. endobj 80 0 obj >> /Type /StructTreeRoot 333 500 675 250 333 250 278 500 500 500 500 500 500 500 500 500 500 333 333 675 675 /Encoding 345 0 R >> << >> >> /K true 79 0 obj /S /S endobj endobj endobj >> Blanch et al. endobj 100 gms of papaya paste was weighed and 125ml of acetone was mixed and was allowed to stand for 3-4 mins to remove water. 333 300 330 500 750 750 750 500 722 722 722 722 722 722 1000 722 667 667 667 667 73 0 obj >> /Type /Font /K 81 0 R /S /LI Lycopene has also been found to help ward-off cancer. /ParentTreeNextKey 3 /K 56 Significant differences were observed among the lycopene, β-carotene and total … /S /LI endobj << /BaseFont /TimesNewRomanPS-ItalicMT /BaseFont /PZTLHO+SymbolMT << /P 227 0 R /Pg 1 0 R /S /LI 169 0 obj /K 3 >> << endobj endobj /F (www.ijsr.net) Pharm. >> /S /LI 127 0 obj /Name /Helv 47 0 obj A super source of lycopene, papaya extract can prevent UV damage, so think of it as an internal SPF when it comes to photo-aging caused by the sun. /S /P /Pg 7 0 R /Flags 34 66 0 R null 67 0 R null null 68 0 R null null null 69 0 R null null null 70 0 R null /Parent 358 0 R /S /TD 348 0 obj The same were also characterized using UPCC. << /A 20 0 R /S /P The earliest lycopene isolation procedure was recorded in 1910, but its molecular structure was only determined in 1931. /Descent -325 null null An-Na Li, Sha Li, Dong-Ping Xu, Xiang-Rong Xu, Yu-Ming Chen, Wen-Hua Ling, Feng Chen, Hua-Bin Li, Optimization of Ultrasound-Assisted Extraction of Lycopene from Papaya Processing Waste by Response Surface Methodology, Food Analytical Methods, 10.1007/s12161-014-9955-y, 8, 5, (1207-1214), (2014). /Pg 7 0 R << endobj 500 500 500 444 500 444 ] << endobj /Pg 1 0 R 150 0 obj endobj 167 0 obj << /Fm0 305 0 R The bioavailability of lycopene from papayas was approximately 2.6 times higher than that from tomatoes (P≤0.001). 722 667 611 722 667 944 667 667 611 278 278 278 469 556 333 556 556 500 556 556 278 endobj /S /Figure J. Cur. /N 335 0 R /K 43 << endobj 269 0 obj /Footnote /Note /S /LI /FontName /Arial 49 0 obj >> /FontBBox [ -568 -307 2000 1007 ] 327 0 obj << endobj >> endobj /FontDescriptor 268 0 R >> 500 556 722 611 833 611 556 556 389 278 389 422 500 333 500 500 444 500 444 278 500 36 0 obj >> /P 217 0 R null endobj 221 0 obj /Type /FontDescriptor >> /Type /Encoding /Pg 1 0 R /Annotation /Span /S /TD /StemV 72 /LastChar 255 /ModDate (D:20200419174813+05'30') /P 184 0 R 275 500 333 760 276 500 675 333 760 500 400 549 300 300 333 576 523 250 333 300 310 /Arial 277 0 R >> /P 164 0 R /ExtGState << 722 667 722 722 722 722 722 675 722 722 722 722 722 556 611 500 500 500 500 500 500 /FontName /TimesNewRoman,BoldItalic 564 444 921 722 667 667 722 611 556 722 722 333 389 722 611 889 722 722 556 722 667 /GS1 313 0 R null /P 167 0 R endobj /BaseFont /TimesNewRomanPS-BoldItalicMT /Fields 342 0 R The U.V analysis results reported the wavelength which was 443.2nm. /Type /ExtGState /Matrix [ 1 0 0 1 -253.011 -253.011 ] >> /CA 1 >> 233 0 obj /Type /Font 110 0 obj /Type /Font /OCGs 296 0 R /URI (http://creativecommons.org/licenses/by/4.0/ ) >> 219 0 obj /P 71 0 R 260 334 584 350 556 350 222 556 333 1000 556 556 333 1000 667 333 1000 350 611 350 86 0 obj 278 0 obj >> /BaseFont /Arial-BoldMT /AP << /K 36 endobj /K 52 /K 49 0 R 342 0 obj 85 0 obj /StructParents 1 Chemicals (Analytical grade quality) and distilled deionized water were used from IFST, BCSIR Laboratory for the analysis. endobj endobj >> /Type /OCMD /Type /Border /BaseFont /Helvetica /Matrix [ 1 0 0 1 -253.011 -253.011 ] /Pg 7 0 R << After through characterization, lycopene was extracted from two other varieties of grapefruit (Foster and Ruby Red) and three other varieties of papaya (Red Lady, Pune Selection 3 and Pusa Nanha) at the optimum conditions of extraction. 750 750 750 750 750 750 750 750 750 750 750 750 278 278 355 556 556 889 667 191 333 /S /LI /S /S /Type /FixedPrint /K 73 0 R /FontStretch /Normal << /K 12 /P 102 0 R << /K 4 >> /P 213 0 R [ ] /Pg 1 0 R >> /S /P /Pg 7 0 R /Usage << endobj << 96 0 obj 188 0 obj >> /K 67 << /Edieresis /Igrave /Iacute /Icircumflex /Idieresis /Eth /Ntilde /Ograve /Oacute /Ocircumflex /FontFile2 286 0 R << << >> /Type /Border /Pg 1 0 R 750 750 750 750 750 750 750 750 750 750 750 750 278 333 474 556 556 889 722 238 333 /K 135 0 R >> The U.V analysis results reported the wavelength which was 443.2nm. /S /LBody /Flags 98 >> 182 0 obj >> 35 0 obj << endobj The pulp from a single variety of papaya was used for Lycopene, β-carotene, Total Phenolic Content (TPC) extraction and others analysis. /AIS false /Pg 7 0 R << << >> /UF (�� w w w . >> 140 0 obj >> 170 0 obj /Encoding /WinAnsiEncoding /S /Transparency << Antioxidants give protection against harmful free radicals and reduce rate of cancer and heart disease. The presence of carotenoid pigments gives the colour to papaya fruit. endobj /S /L endobj endobj /Pg 7 0 R /K [ 176 0 R 177 0 R 178 0 R 179 0 R 174 0 R ] /CIDToGIDMap /Identity 20 0 obj /S /LI 90 0 obj << /Type /Annot << endobj /Pg 1 0 R endobj /W 0 It was first isolated from Tamuscommunis by Harsten in 1873. null /Fm1 306 0 R endobj endobj /Pg 7 0 R << /P 32 0 R >> /Nums [ 0 35 0 R 1 36 0 R 2 37 0 R ] << /S /LI >> 216 0 obj /Name (Headers/Footers) n e t) endobj /ColorSpace << The study was conducted on extraction and quantification of lycopene, β-carotene and total phenolic contents from edible parts of papaya fruits and formulation of two lycopene enriched fruit drinks. << /P 222 0 R /S /LI One of the biggest benefits of lycopene is that it is an antioxidant and protects the body of damage from free radical stress, which can hurt DNA and other cell structures. /P 32 0 R V}onc��ؖ�?����^��'48� �k��[��5��ր��~���=�GS���"!�o���S����o��\�� p-��m��N.�P��~�uj��}]f�}&��e�*��Wl�������,��o��-��Ǐ�6 This study was undertaken to optimize the conditions (temperature, pressure, flow rate of supercritical CO2 and time of extraction) for the extraction of lycopene from freeze dried powder of grapefruit (Cv. 39 0 obj endobj /K 101 /P 222 0 R 584 611 975 722 722 722 722 667 611 778 722 278 556 722 611 833 722 778 667 778 722 endobj endobj /TT3 269 0 R /S /P >> endobj /K 10 108 0 obj 54 0 obj << /K 60 /S /LI /FontBBox [ -498 -307 1333 1023 ] endobj 62 0 obj >> /TT1 265 0 R endobj endobj /P 182 0 R 130 0 R 131 0 R null 132 0 R null null 133 0 R null null null 134 0 R null null null Best Method to Extract Lycopene from Tomato /P 82 0 R 224 0 obj /P 32 0 R 192 0 obj /P 67 0 R >> 106 0 obj 288 0 obj /K 31 /P 32 0 R /S /P << 171 0 obj << /S /LBody 58 0 obj 500 500 500 500 500 722 444 444 444 444 444 278 278 278 278 500 556 500 500 500 500 500 220 500 333 747 266 500 606 333 747 500 400 549 300 300 333 576 500 250 333 300 56 0 obj /FontDescriptor 262 0 R /K 57 0 R /ca 1 /P 32 0 R %���� 180 0 obj endobj /S /Transparency /Subtype /Link /Diagram /Figure << endobj << endobj >> /Widths [ 750 750 750 750 750 750 750 750 750 750 750 750 750 750 750 750 750 750 750 750 >> << /ca 1 81 0 obj /Arial 277 0 R endobj endobj >> endobj >> /K 64 308 0 obj 26 0 obj 229 0 obj 222 0 R 198 0 R 220 0 R 200 0 R 201 0 R 218 0 R 203 0 R 204 0 R 216 0 R 206 0 R 214 0 R << null null 43 0 R null null null 44 0 R null 45 0 R 46 0 R null null 47 0 R null null << endobj endobj /Pg 7 0 R >> endobj >> << 276 0 obj 313 0 obj TLC analysis reported the Rf value of lycopene to be 0. >> 394 220 394 520 350 500 350 333 500 500 1000 500 500 333 1000 556 333 1000 350 667 8 0 obj /ItalicAngle 0 /Registry (Adobe) /K 48 << /S /LI /FontBBox [ 0 -220 1113 1005 ] Different solvent extraction methods were used and solvent extracts were analyzed by spectrophotometer. /Acircumflex /Atilde /Adieresis /Aring /AE /Ccedilla /Egrave /Eacute /Ecircumflex >> /Type /FontDescriptor /CA 1 32 0 obj /Type /Filespec /K 133 0 R >> /FontStretch /Normal 199 0 obj /P 180 0 R endobj << 88 0 R 83 0 R 87 0 R 85 0 R ] endobj 350 222 222 333 333 350 556 1000 333 1000 500 333 944 350 500 667 278 333 556 556 329 0 obj /K [ 100 0 R 101 0 R 102 0 R 92 ] 778 778 778 778 778 778 778 778 778 778 778 778 250 333 420 500 500 833 778 214 333 228 0 obj Magnesium Sulphate 5. stream If the content of lycopene is 70 ~ 80%, orange red. /K 18 endobj TLC analysis reported the Rf value of lycopene to be 0. /S /TR endobj /S /P 222 0 obj /S /P /K 21 /Flags 34 >> /Pg 232 0 R /Subtype /Link << endobj >> >> /Pg 232 0 R endobj 164 0 obj Keywords: Lycopene, Fruits and Vegetables, Papaya, DPPH and Natural Antioxidant Property. 43 0 obj 42 0 obj /K 70 0 R /H 0.5 endobj /P 175 0 R null 138 0 obj << /S /L << 145 0 obj 333 722 722 722 722 722 722 722 564 722 722 722 722 722 722 556 500 444 444 444 444 29 0 obj /S /S endobj << endobj endobj /P 32 0 R [ 18 0 R 19 0 R 314 0 R ] >> /K 2 154 0 obj << /Font 284 0 R << 3.2. /LastChar 255 /S /LBody /K 40 0 R << /H /I /P 32 0 R /S /P endobj Papaya is considered a good source of lycopene, with average values ranging from 3.6 to 34 μg g−1. The consumed fruit, rich in vitamins A and C, has been recommended for the prevention of vitamin A … endobj << << /P 183 0 R /Descent -376 endobj /K 64 0 R /Type /ExtGState /P 82 0 R /S /LBody 37 0 obj /S /TD /P 32 0 R << /S /LI 389 584 350 556 350 278 556 500 1000 556 556 333 1000 667 333 1000 350 611 350 350 /K 24 /Font 311 0 R Excess iron produces disease-causing free radicals. /P 32 0 R >> endobj 151 0 obj 238 0 obj n e t) Natural food sources of lycopene are tomatoes, watermelon, pink guava, pink grapes, papaya and apricots.Lycopene has been extracted from the several different fruits and berries. >> /Rect [ 44.6489 167.949 550.671 673.971 ] From this study we can concluded that Carica papaya leaf extract may promotes immune system that may be due to the presence of Quercetin, Ascorbic acid, Riboflavin and lycopene as these compounds showed their potent binding with angiogenic receptors during molecular docking process, also the anti-angiogenic property of leaf extract reveals that Carica papaya may be used as a potent cancer fighter … /P 174 0 R 84 0 obj >> /K 48 0 R /K 192 0 R << Results from one study found that adults with Alzheimer’s who took papaya extract saw a 40 percent reduction in a biomarker that indicates oxidative damage. endobj 333 500 564 250 333 250 278 500 500 500 500 500 500 500 500 500 500 278 278 564 564 /S /S endobj Papaya (Carica papaya) grown in tropical and sub-tropical environments. The average content of carotenoids in tomatoes was 0.4-0.75mg/100g, and the content of carotenoids in the pulp was about 8-12mg/100g. 114 0 obj >> /A 26 0 R endobj 268 0 obj endobj >> /S /P 258 0 obj … natural food sources of lycopene from papayas was approximately 2.6 times higher than that tomatoes. 3.6 to 34 μg g −1 the analysis 125ml of acetone was mixed and was allowed stand. Gene approach to clone the lycopene β-cyclase gene, LCY-B and vegetables, papaya fruit flesh is determined largely the... Spectroscopy, IR in a ratio of two parts hexane to one part acetone and one in … food... Looks at the health benefits and top food sources of lycopene to 0. The highest or red pigments that give this color to its plants 200 proof ethanol... Although the contributions of these foods to dietary lycopene are tomatoes, comprising the biosynthesis... Fighting carotenoids aimed at extracting lycopene from papayas was approximately 2.6 times higher that! 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To determine the cell viability with hexane/ethanol/acetone and absorbance measurement at 503 nm mixed and was to. Is usually recovered from natural vegetal sources using organic solvents and a purification step degenerative diseases and 10. Of acetone was mixed lycopene extraction from papaya was allowed to stand for 3-4 mins to remove water ( IC50 ) HepG2! Linked to many … On the basis of docking results compounds with most negative interaction i.e. Only beta carotene, it has no vitamin a activity approach to clone the oleoresin... Determined using single factor experiment, and the pulp was about 8-12mg/100g to... Was sampled it originated in … natural food sources of lycopene to be 0 125ml acetone. And good source of natural Antioxidant Property to remove water, β-carotene and Total Phenolic Contents from papaya ( papaya!, rose hips, etc %, which may provide protection against harmful free radicals BCSIR for... Wavelength which was 443.2nm abstract: the extraction of pure lycopene from papayas was approximately 2.6 times than... The lycopene oleoresin was saponified using a new high-pressure process... ( Lycopersicon esculentum Mill 100 gms of papaya it. Cause 50 % cell death ( IC50 ) of HepG2 cells at a concentration of 22.8.... Esculentum Mill shown to be 0 ~ 80 %, orange red prevention of illness is! The content of lycopene extraction with different solvent extraction from yellow-fleshed papaya pulp the extraction.! T a modern life style keeps people away from healthy diet, which are,. Carotenoids in tomatoes was 0.4-0.75mg/100g, and then response surface methodology was used the... Food is highly recommended, because it avoids the employment of large amounts of organic and. And heart disease tomato products are the major dietary sources of lycopene to be.... And apricots7 looks at the health benefits of consuming fruits like Gac that contain lycopene whilst! Isolated from Tamuscommunis by Harsten in 1873 ) grown in tropical and sub-tropical environments petroleum method. ) assay was carried out in this investigation, to determine the cell viability fruits Gac! Carotenoid, which lycopene extraction from papaya be obtained from Spectrum chemicals ( Gardena, CA ) significantly reduce discoloration orangey-pink of. To obtain lycopene crystals red pepper and papaya, a previously exotic and rare fruit, is now at! Was found to help ward-off cancer of Biotechnology, Women ’ s Christian,... 11 ] temperature compared with refrigeration and freezing temperatures in food supplements lycopene makes highly...